Exploration Deficits Under Ecological Conditions as a Marker of Apathy in Frontotemporal Dementia.

ABSTRACT: Apathy is one of the six clinical criteria for the behavioral variant of frontotemporal dementia (bvFTD), and it is almost universal in this disease. Although its consequences in everyday life are debilitating, its underlying mechanisms are poorly known, its assessment is biased by subjectivity and its care management is very limited. In this context, we have developed "ECOCAPTURE," a method aimed at providing quantifiable and objective signature(s) of apathy in order to assess it and identify its precise underlying mechanisms. ECOCAPTURE consists of the observation and recording of the patient's behavior when the participant is being submitted to a multiple-phase scenario reproducing a brief real-life situation. It is performed in a functional exploration platform transforme

SUBMITTER: Batrancourt B 

PROVIDER: S-EPMC6736613 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature