Association of MRI T2 Signal Intensity With Desmoid Tumor Progression During Active Observation: A Retrospective Cohort Study.

ABSTRACT:

Objective

The aim of this study was to identify predictors of desmoid progression during observation.

Summary of background data

Untreated desmoids can grow, remain stable, or regress, but reliable predictors of behavior have not been identified.

Methods

Primary or recurrent desmoid patients were identified retrospectively from an institutional database. In those managed with active observation who underwent serial magnetic resonance imaging (MRIs) with T2-weighted sequences, baseline tumor size was recorded, and 2 radiologists independently estimated the percentage of tumor volume showing hyperintense T2 signal at baseline. Associations of clinical or radiographic characteristics with progression-free survival (PFS; by RECIST) were evaluated by Cox regression and Kap

SUBMITTER: Cassidy MR 

PROVIDER: S-EPMC6736761 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature