Sensing by wireless reading Ag/AgCl redox conversion on RFID tag: universal, battery-less biosensor design.

ABSTRACT: Massive integration of biosensors into design of Internet-of-Things (IoT) is vital for progress of healthcare. However, the integration of biosensors is challenging due to limited availability of battery-less biosensor designs. In this work, a combination of nanomaterials for wireless sensing of biological redox reactions is described. The design exploits silver nanoparticles (AgNPs) as part of the RFID tag antenna. We demonstrate that a redox enzyme, particularly, horseradish peroxidase (HRP), can convert AgNPs into AgCl in the presence of its substrate, hydrogen peroxide. This strongly changes the impedance of the tag. The presented example exploits gold nanoparticle (AuNP)-assisted electron transfer (ET) between AgNPs and HRP. We show that AuNP is a vital intermediate for establishing r

SUBMITTER: Larpant N 

PROVIDER: S-EPMC6736964 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature