Penile cancer with positive nodes: A case of HPV p16-positivity and its significance, implication of data from head and neck cancer.

ABSTRACT: Penile cancer is normally discovered in an early stage due to its visibility to the patient. This case report demonstrates a morbidly obese patient with a locally advanced penile cancer hidden by fatty tissue. Biopsy showed P16-positive tumor cells, which responded to concurrent chemo-radiotherapy with no evidence of disease at 24 months of follow-up. We also review the significance of p16-positive cell biology.

SUBMITTER: Nguyen C 

PROVIDER: S-EPMC6737329 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature