Emergence of IncX3 Plasmid-Harboring bla _{NDM- 5} Dominated by Escherichia coli ST48 in a Goose Farm in Jiangsu, China.

ABSTRACT: Twelve carbapenem-resistant Escherichia coli strains were obtained from goose farms in Jiangsu, China. These isolates were resistant to multiple antimicrobials, and positive for the bla _{NDM- 5}. The carbapenem-resistance of all strains mediated by bla _{NDM- 5} were successfully conjugated to E. coli J53. S1-PFGE and WGS results showed bla _{NDM- 5} was located on IncX3 conjugative plasmids with a size of ca. 46 kb. All bla _{NDM- 5}-bearing IncX3 plasmids shared the same genetic context almost identical to pNDM_MGR194-bla _{NDM- 5} and pNDM-QD28-bla _{NDM- 5} reported in India and China, respectively. The twelve strains

SUBMITTER: Liu Z 

PROVIDER: S-EPMC6737504 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature