Nitromethane Exposure from Tobacco Smoke and Diet in the U.S. Population: NHANES, 2007-2012.

ABSTRACT: Nitromethane is a known toxicant and suspected human carcinogen. Exposure to nitromethane in a representative sample of the civilian, noninstitutionalized population in the United States ≥12 years old was assessed using 2007-2012 National Health and Nutritional Examination Survey (NHANES) data. Nitromethane was detected in all 8000 human blood samples collected, of which 6730 were used for analyses reported here. Sample-weighted median blood nitromethane was higher among exclusive combusted tobacco users (exclusive smokers; 774 ng/L) than nonusers of tobacco products (625 ng/L). In stratified sample-weighted regression analysis, smoking 0.5 pack of cigarettes per day was associated with a statistically significant increase in blood nitromethane by 150 ng/L, and secondhand smoke exposure (s

SUBMITTER: Espenship MF 

PROVIDER: S-EPMC6737526 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature