DnAQET: a framework to compute a consolidated metric for benchmarking quality of de novo assemblies.

ABSTRACT:

Background

Accurate de novo genome assembly has become reality with the advancements in sequencing technology. With the ever-increasing number of de novo genome assembly tools, assessing the quality of assemblies has become of great importance in genome research. Although many quality metrics have been proposed and software tools for calculating those metrics have been developed, the existing tools do not produce a unified measure to reflect the overall quality of an assembly.

Results

To address this issue, we developed the de novo Assembly Quality Evaluation Tool (dnAQET) that generates a unified metric for benchmarking the quality assessment of assemblies. Our framework first calculates individual quality scores for the scaffolds/contigs of an assembly by aligning them to

SUBMITTER: Yavas G 

PROVIDER: S-EPMC6737619 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature