Different levels of cardiometabolic indicators in multiple vs. singleton children.

ABSTRACT:

Background

We aimed to compare cardiometabolic indicators in singletons and multiples at age 7 and explore the birthweight mediation effect.

Methods

We studied 5431 singletons and 103 sets of multiples from Generation XXI birth cohort. Anthropometric measurements, body composition, and fasting blood samples were obtained. Age- and sex-specific z-scores were calculated (additionally height-specific for blood pressure). Adjusted regression coefficients and respective 95% confidence intervals [β (95%CI)] were computed using path analysis.

Results

Multiples had lower weight [- 0.419 (- 0.616;-0.223)], height [- 0.404 (- 0.594;-0.213)], BMI [- 0.470 (- 0.705;-0.234)], fat mass index [- 0.359 (- 0.565;-0.152)], waist circumference [- 0.342 (- 0.537;-0.147)], and waist-to-he

SUBMITTER: Fonseca MJ 

PROVIDER: S-EPMC6737661 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature