Higher interleukin-33 levels in aggressive periodontitis cases.

ABSTRACT:

Context

Interleukin-33 (IL-33) is a novel alarmin that warns immune cells of tissue destruction in injury or infection.

Aims

This study is aimed at analyzing and correlating the concentration of IL-33 in the gingival crevicular fluid (GCF) and plasma of healthy subjects and chronic and aggressive periodontitis patients with intronic variant single nucleotide polymorphisms (SNPs), rs1157505 (C/G) and rs7044343 (C/T) in the IL-33 gene.

Settings and design

This is a cross-sectional, biochemical, genetic study.

Materials and methods

Ninety subjects were divided into Group H: subjects with healthy periodontium, Group CP: chronic periodontitis patients, and Group GAgP: generalized aggressive periodontitis patients, based on clinical parameters of periodontal inflamma

SUBMITTER: Ballambettu SP 

PROVIDER: S-EPMC6737856 | biostudies-literature | 2019 Sep-Oct

REPOSITORIES: biostudies-literature