Iron stores in pregnant women with sickle cell disease: a protocol for a systematic review and meta-analysis.

ABSTRACT:

Introduction

Sickle cell disease (SCD) is the most common inherited disease worldwide. The greatest disease burden is seen in sub-Saharan Africa. Early diagnosis and improved care of people living with SCD have led to an increase in the number of women with SCD reaching the reproductive age. Iron deficiency anaemia remains the most common cause of anaemia in pregnancy, affecting 51%-63% of pregnancies in Africa. However, the unavailability of guidelines on supplementation of iron in this pregnant subpopulation often leaves clinicians in a fix. We propose to conduct the first systematic review and possibly a meta-analysis on the prevalence, associated factors and maternal/fetal outcomes of iron deficiency anaemia among pregnant women with SCD.

Methods and analysis

We will sea

SUBMITTER: Aroke D 

PROVIDER: S-EPMC6738703 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature