Comparative efficacy of 13 immunosuppressive agents for idiopathic membranous nephropathy in adults with nephrotic syndrome: a systematic review and network meta-analysis.

ABSTRACT:

Objectives

This study aimed to compare the effectiveness of 13 types of immunosuppressive agents used to treat idiopathic membranous nephropathy (IMN) in adults with nephrotic syndrome.

Design

Systematic review and network meta-analysis.

Data sources

PubMed, EMbase, Cochrane Library, Web of Science, Clinical trials, SinoMed, Chinese Biomedicine, CNKI, WanFang and Chongqing VIP Information databases were comprehensively searched until February 2018.

Eligibility criteria

Randomised clinical trials (RCTs) comparing the effects of different immunosuppressive treatments in adult patients with IMN and nephrotic syndrome were included, and all included RCTs had a study-duration of at least 6 months.

Data extraction and synthesis

Two reviewers independently scre

SUBMITTER: Zheng Q 

PROVIDER: S-EPMC6738938 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature