Understanding Aging in Bipolar Disorder by Integrating Archival Clinical Research Datasets.

ABSTRACT:

Objective

Although 25% of people with bipolar disorder (BD) are over age 60, there is a dearth of research on older age bipolar disorder (OABD). This report describes an initial effort to create an integrated OABD database using the U.S. National Institute of Mental Health Data Archive (NDA). Goals were to: 1) combine data from three BD studies in the United States that included overlapping data elements; 2) investigate research questions related to aims of the original studies; and 3) take an important first step toward combining existing datasets relevant to aging and BD.

Methods

Data were prepared and uploaded to the NDA, with a focus on data elements common to all studies. As appropriate, data were harmonized to select or collapse categories suitable for cross-walk analy

SUBMITTER: Eyler LT 

PROVIDER: S-EPMC6739177 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature