Light-inducible carotenoid production controlled by a MarR-type regulator in Corynebacterium glutamicum.

ABSTRACT: Carotenoid production in some non-phototropic bacteria occurs in a light-dependent manner to protect cells from photo-oxidants. Knowledge regarding the transcriptional regulator involved in the light-dependent production of carotenoids of non-phototrophic bacteria has been mainly confined to coenzyme B₁₂-based photo-sensitive regulator CarH/LitR family proteins belonging to a MerR family transcriptional regulator. In this study, we found that bacteria belonging to Micrococcales and Corynebacteriales exhibit light-dependent carotenoid-like pigment production including an amino acid-producer Corynebacterium glutamicum AJ1511. CrtR is a putative MarR family transcriptional regulator located in the divergent region of a carotenoid biosynthesis gene cluster in the genome of those bac

SUBMITTER: Sumi S 

PROVIDER: S-EPMC6739363 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature