Impact of One-Health framework on vaccination cost-effectiveness: A case study of rabies in Ethiopia.

ABSTRACT: Livestock losses due to rabies and health and the corresponding benefits of controlling the disease are not often considered when the cost-effectiveness of rabies control is evaluated. In this research, assessed the benefits of applying a One Health perspective that includes these losses to the case of canine rabies vaccination in Ethiopia. We constructed a dynamic epidemiological model of rabies transmission. The model was fit to district-specific data on human rabies exposures and canine demography for two districts with distinct agro-ecologies. The epidemiological model was coupled with human and livestock economic outcomes to predict the health and economic impacts under a range of vaccination scenarios. The model indicates that human exposures, human deaths, and rabies-related livesto

SUBMITTER: Beyene TJ 

PROVIDER: S-EPMC6739487 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature