Topical hydrogel containing Fumaria vaillantii Loisel. extract enhances wound healing in rats.

ABSTRACT:

Background

Fumaria species (Fumariacea) has traditionally been used in wound healing in Iranian folk medicine. However, with the discovery of newer agents, its use has faded off into total obscurity. This study explored the wound healing potential of a gel containing 10% Fumaria vaillantii Loisel through topical application of total extract in a model of excisional as well as incisional wound healing in albino Wistar rats.

Methods

Rats were anesthetized, and excisional skin wound was established using a sterilized surgical scissors. The animals were then treated with 10% F.vaillantii topical gel formulation along with the gel base. The treatments were administered once a day after the injury for 21 days. For topical treatment, the hydrogel was formulated and evaluated for ch

SUBMITTER: Davoodi-Roodbordeii F 

PROVIDER: S-EPMC6739951 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature