Long-term dynamics of measles in London: Titrating the impact of wars, the 1918 pandemic, and vaccination.

ABSTRACT: A key question in ecology is the relative impact of internal nonlinear dynamics and external perturbations on the long-term trajectories of natural systems. Measles has been analyzed extensively as a paradigm for consumer-resource dynamics due to the oscillatory nature of the host-pathogen life cycle, the abundance of rich data to test theory, and public health relevance. The dynamics of measles in London, in particular, has acted as a prototypical test bed for such analysis using incidence data from the pre-vaccination era (1944-1967). However, during this timeframe there were few external large-scale perturbations, limiting an assessment of the relative impact of internal and extra demographic perturbations to the host population. Here, we extended the previous London analyses to include

SUBMITTER: Becker AD 

PROVIDER: S-EPMC6742223 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature