Association between coffee consumption and risk of bladder cancer in a meta-analysis of 16 prospective studies.

ABSTRACT:

Background

Current evidence remains equivocal as to whether and how consumption of coffee may be associated with risk of bladder cancer, and potential influence of confounding by smoking on this association is yet to be elucidated. We conducted an updated meta-analysis of prospective studies to address these issues.

Methods

Relevant studies were identified by searching PubMed and EMBASE databases from inception to April 2019. A random-effects model was used to estimate summary relative risk (RR) with corresponding 95% confidence interval (CI) of bladder cancer associated with coffee consumption.

Results

The final analysis included 16 prospective studies comprising 2,122,816 participants and 11,848 bladder cancer cases. Overall, coffee consumption was not associated wi

SUBMITTER: Dai ZW 

PROVIDER: S-EPMC6743122 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature