Cross-sectional HIV incidence estimation in an evolving epidemic.

ABSTRACT: The cross-sectional approach to HIV incidence estimation overcomes some of the challenges with longitudinal cohort studies and has been successfully applied in many settings around the world. However, the cross-sectional approach does rely on an initial training data set to develop and calibrate the statistical methods to be used in cross-sectional surveys. The problem addressed in this paper is that the initial training data set may, over time, not reflect the current target population of interest because of evolution of the epidemic. For example, the mismatch between the target population and the initial data set could occur because of increasing use of anti-retroviral therapy among HIV-infected persons throughout the world. We developed methods to adjust the initial training data set wi

SUBMITTER: Morrison D 

PROVIDER: S-EPMC6743486 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature