Robust pCASL perfusion imaging using a 3D Cartesian acquisition with spiral profile reordering (CASPR).

ABSTRACT:

Purpose

To improve the robustness of arterial spin-labeled measured perfusion using a novel Cartesian acquisition with spiral profile reordering (CASPR) 3D turbo spin echo (TSE) in the brain and kidneys.

Methods

The CASPR view ordering followed a pseudo-spiral trajectory on a Cartesian grid, by sampling the center of k-space at the beginning of each echo train of a segmented 3D TSE acquisition. With institutional review board approval and written informed consent, 14 normal subjects (9 brain and 5 kidneys) were scanned with pCASL perfusion imaging using 3D CASPR and compared against 3D linear TSE (brain and kidneys), the established 2D EPI and 3D gradient and spin echo perfusion (brain), and 2D single-shot turbo spin-echo perfusion (kidneys). The SNR and the quantitative per

SUBMITTER: Greer JS 

PROVIDER: S-EPMC6743738 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature