Uric acid within the "normal" range predict 9-year cardiovascular mortality in older individuals. The InCHIANTI study.

ABSTRACT:

Background and aims

Increased uric acid levels correlate with cardiovascular disease and cardiovascular/overall mortality. To identify a uric acid threshold above which cardiovascular mortality rises, we studied the relationship between uric acid concentration and overall/cardiovascular mortality.

Methods and results

We analyzed data from the InCHIANTI study, a cohort study of Italian community-dwelling people with 9 years of follow-up. We selected a sample of 947 individuals over 64 years of age, free from cardio-cerebrovascular disease and with available uric acid measurement at baseline. The sample was divided according to plasma uric acid tertiles. The Hazard ratio (HR) for mortality was calculated by multivariate Cox proportional hazard model. Mean age of participants w

SUBMITTER: Brombo G 

PROVIDER: S-EPMC6744329 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature