Reasons for Differences in the Incidence of Venous Thromboembolism in Black Versus White Americans.

ABSTRACT:

Introduction

Venous thromboembolism incidence rates are 30%-100% higher in US blacks than whites. We examined the degree to which differences in the frequencies of socioeconomic, lifestyle, medical risk factors, and genetic variants explain the excess venous thromboembolism risk in blacks and whether some risk factors are more strongly associated with venous thromboembolism in blacks compared with whites.

Methods

We measured venous thromboembolism risk factors in black and white participants of the Atherosclerosis Risk in Communities study in 1987-1989 and followed them prospectively through 2015 for venous thromboembolism incidence.

Results

Over a mean of 22 years, we identified 332 venous thromboembolisms in blacks and 578 in whites, yielding 65% higher crude incide

SUBMITTER: Folsom AR 

PROVIDER: S-EPMC6744355 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature