Patient-reported outcomes in randomised clinical trials of bladder cancer: an updated systematic review.

ABSTRACT:

Background

Despite international recommendations of including patient-reported outcomes (PROs) in randomised clinical trials (RCTs), a 2014 review concluded that few RCTs of bladder cancer (BC) report PRO as an outcome. We therefore aimed to update the 2014 review to synthesise current evidence-based knowledge of PROs from RCTs in BC. A secondary objective was to examine whether quality of PRO reporting has improved over time and to provide evidence-based recommendations for future studies in this area.

Methods

We conducted a systematic literature search using PubMed/Medline, from April 2014 until June 2018. We included the RCTs identified in the previous review as well as newly published RCTs. Studies were evaluated using a predefined electronic-data extraction form that in

SUBMITTER: Van Hemelrijck M 

PROVIDER: S-EPMC6744649 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature