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Interleukin-10 (1082G/A) Polymorphism is Associated with Susceptibility of Acute Myeloid Leukemia Patients in Sudanese Population.


ABSTRACT: Background: Interleukin-10 (IL-10) is a multifunctional cytokine with both immunosuppressive and antiangiogenicfunctions

SUBMITTER: Sharif OM 

PROVIDER: S-EPMC6745212 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature

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Interleukin-10 (1082G/A) Polymorphism is Associated with Susceptibility of Acute Myeloid Leukemia Patients in Sudanese Population.

Sharif Omnia Mohamed OM   Hassan Rosline R   Mohammed Basbaeen Ameen Abdulaziz AA   Mohmed Ayman Hussien AH   Ibrahim Ibrahim Khider IK  

Asian Pacific journal of cancer prevention : APJCP 20190701 7


Background: Interleukin-10 (IL-10) is a multifunctional cytokine with both immunosuppressive and antiangiogenicfunctions and may have both tumor-promoting and -inhibiting properties. We examined the association between a single nucleotide polymorphism (SNP) in IL-10 -1082G/A (rs1800896) in Sudanese acute myeloid leukemia (AML) patients and to assess the association between polymorphisms in IL-10 -1082G/A (rs1800896) and the hematological profile in Sudanese patients with AML. Methods: A total of  ...[more]

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