Diagnostic Test Score Validation With a Fallible Criterion.

ABSTRACT: Criterion-related validation of diagnostic test scores for a construct of interest is complicated by the unavailability of the construct directly. The standard method, Known Group Validation, assumes an infallible reference test in place of the construct, but infallible reference tests are rare. In contrast, Mixed Group Validation allows for a fallible reference test, but has been found to make strong assumptions not appropriate for the majority of diagnostic test validation studies. The Neighborhood model is adapted for the purpose of diagnostic test validation, which makes alternate, but also strong, assumptions. The statistical properties of the Neighborhood model are evaluated and the assumptions are reviewed in the context of diagnostic test validation. Alternatively, strong assumptio

SUBMITTER: Jewsbury PA 

PROVIDER: S-EPMC6745629 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature