Heterogeneity in transmission parameters of hookworm infection within the baseline data from the TUMIKIA study in Kenya.

ABSTRACT:

Background

As many countries with endemic soil-transmitted helminth (STH) burdens achieve high coverage levels of mass drug administration (MDA) to treat school-aged and pre-school-aged children, understanding the detailed effects of MDA on the epidemiology of STH infections is desirable in formulating future policies for morbidity and/or transmission control. Prevalence and mean intensity of infection are characterized by heterogeneity across a region, leading to uncertainty in the impact of MDA strategies. In this paper, we analyze this heterogeneity in terms of factors that govern the transmission dynamics of the parasite in the host population.

Results

Using data from the TUMIKIA study in Kenya (cluster STH prevalence range at baseline: 0-63%), we estimated these paramet

SUBMITTER: Truscott JE 

PROVIDER: S-EPMC6745791 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature