Cancer Outcomes in DCIS Patients Without Locoregional Treatment.

ABSTRACT:

Background

The vast majority of women diagnosed with ductal carcinoma in situ (DCIS) undergo treatment. Therefore, the risks of invasive progression and competing death in the absence of locoregional therapy are uncertain.

Methods

We performed survival analyses of patient-level data from DCIS patients who did not receive definitive surgery or radiation therapy as recorded in the US National Cancer Institute's Surveillance, Epidemiology, and End Results program (1992-2014). Kaplan-Meier curves were used to estimate the net risk of subsequent ipsilateral invasive cancer. The cumulative incidences of ipsilateral invasive cancer, contralateral breast cancer, and death were estimated using competing risk methods.

Results

A total of 1286 DCIS patients who did not undergo lo

SUBMITTER: Ryser MD 

PROVIDER: S-EPMC6748726 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature