Cost-Effectiveness Analysis of Influenza A (H1N1) Chemoprophylaxis in Brazil.

ABSTRACT: Background: Oseltamivir and zanamivir are recommended for treating and preventing influenza A (H1N1) worldwide. In Brazil, this official recommendation lacks an economic evaluation. Our objective was to assess the efficiency of influenza A chemoprophylaxis in the Brazilian context. Methods: We assessed the cost-effectiveness of oseltamivir and zanamivir for prophylaxis of influenza for high risk population, compared to no prophylaxis, in the perspective of Brazilian public health system. Quality-adjusted life years (QALY) and effectiveness data were based on literature review and costs in Brazilian real (BRL) were estimated from official sources and micro-costing of 2016's H1N1 admissions at a university hospital. We used a decision-tree model considering prophylaxis and no p

SUBMITTER: Vecoso LVZ 

PROVIDER: S-EPMC6749104 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature