Analysis of Hepatitis B Virus Reactivation After Radiotherapy in Patients With Hepatocellular Carcinoma Using the Lyman NTCP Model.

ABSTRACT:

Purpose

To analyze the correlation of hepatitis B virus reactivation with patient-related and treatment-related dose-volume factors and to describe the feasibility of hepatitis B virus reactivation analyzed by a normal tissue complication probability model for patients with hepatocellular carcinoma treated with radiotherapy.

Materials and methods

Ninety patients with hepatitis B virus-related hepatocellular carcinoma treated with radiotherapy were enrolled in this retrospective study and were followed from June 2009 to December 2015. Of the 90 patients, 78 had received conventional fractionation radiotherapy to a mean dose of 39.6 to 50.4 Gy and 12 patients were scheduled to receive hypofractionation. The physical doses were converted into 2 Gy equivalents for analysis. The

SUBMITTER: Li Z 

PROVIDER: S-EPMC6749789 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature