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Lurasidone-Induced Tardive Syndrome.


ABSTRACT:

Introduction

Tardive syndrome (TS) is an often irreversible movement disorder caused by dopamine receptor-blocking agents (DRBAs). Although TS are well recognized to occur with typical antipsychotics, less well appreciated is that atypical antipsychotics also carry a risk of TS.

Methods

Case series.

Results

We describe 4 patients who developed tardive dystonia, tardive akathisia, and drug-induced parkinsonism with the use of the atypical antipsychotic, lurasidone, which was U.S. Food and Drug Administration approved in 2013 for use in bipolar disorder and schizophrenia.

Conclusion

Movement disorders are reported as a rare side effect of lurasidone, and, as such, prescribers may perceive a false sense of security regarding this potential complication. Our cases

SUBMITTER: Tripathi R 

PROVIDER: S-EPMC6749798 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature