Combined exposure to lead, cadmium, mercury, and arsenic and kidney health in adolescents age 12-19 in NHANES 2009-2014.

ABSTRACT:

Background

Occupational and environmental exposures to toxic metals are established risk factors for the development of hypertension and kidney disease in adults. There is some evidence of developmental metal nephrotoxicity in children and from animal studies; however, to our knowledge no previous studies have examined associations between co-exposure to nephrotoxic environmental metals and children's kidney health.

Objective

The objective of this study was to assess the association between co-exposure to lead (Pb), cadmium (Cd), mercury (Hg), and arsenic (As), measured in urine and blood, and kidney parameters in US adolescents.

Methods

We performed a cross-sectional analysis of a subsample of 2709 children aged 12-19 participating in the National Health and Nutritio

SUBMITTER: Sanders AP 

PROVIDER: S-EPMC6750805 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature