Multicolor Aptasensor Based on DNA-Induced Au-Ag Nanorods for Simultaneous and Visual Detection of Inorganic and Organic Mercury.

ABSTRACT: Compared to inorganic mercury (Hg2+), methyl-mercury (CH3Hg+) and ethyl-mercury (C2H5Hg+) (organic mercury) not only have a much stronger toxicity but also are more easily accumulated by marine organisms to produce bioamplification. Therefore, the simultaneously onsite detection of Hg2+ and organic mercury is of great significance to ensure the safety of seafood, and it is also a hard challenge. We designed a T-rich aptamer, HT7, for specifically recognizing Hg2+ and organic mercury and developed a multicolor aptasensor for simultaneous discrimination and detection of Hg2+ and organic mercury with only bare-eye observation using HT7 as a recognition probe and gold nanorods (AuNRs) as a signal. In the presence of Hg2+ and Ag+, Hg2+ preferentially and specifically bind with HT7 immobilized o

SUBMITTER: Chen Z 

PROVIDER: S-EPMC6751705 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature