Association of Prenatal Maternal Anemia With Neurodevelopmental Disorders.

ABSTRACT:

Importance

Given the critical role that iron plays in neurodevelopment, an association between prenatal iron deficiency and later risk of neurodevelopmental disorders, such as autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), and intellectual disability (ID), is plausible.

Objective

To test the a priori hypothesis that anemia diagnosed in mothers during pregnancy is associated with an increased risk of ASD, ADHD, and ID in offspring and that the magnitude of the risk varies with regard to the timing of anemia in pregnancy.

Design, setting, and participants

This cohort study used health and population register data from the Stockholm Youth Cohort to evaluate 532 232 nonadoptive children born from January 1, 1987, to December 31, 2010, in

SUBMITTER: Wiegersma AM 

PROVIDER: S-EPMC6751782 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature