Association between Toxoplasma gondii infection and thyroid dysfunction: a case-control seroprevalence study.

ABSTRACT:

Background

The association between Toxoplasma gondii infection and thyroid disease has been poorly studied. Therefore, we sought to determine the association between T. gondii seropositivity and thyroid dysfunction.

Methods

We performed an age- and gender-matched case-control study of 176 patients suffering from hypothyroidism (n = 161) or hyperthyroidism (n = 15) and 528 control subjects without these diseases in a public hospital in Durango City, Mexico. Anti-Toxoplasma IgG antibodies were determined in sera from cases and controls using a commercially available enzyme-linked immunoassay.

Results

Anti-T. gondii IgG antibodies were found in 11 (6.3%) of 176 patients suffering from thyroid dysfunction and in 48 (9.1%) of 528 control subjects (OR = 0.66; 95% CI: 0.33-1

SUBMITTER: Alvarado-Esquivel C 

PROVIDER: S-EPMC6751844 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature