Brain Networks Reveal the Effects of Antipsychotic Drugs on Schizophrenia Patients and Controls.

ABSTRACT: The study of brain networks, including those derived from functional neuroimaging data, attracts a broad interest and represents a rapidly growing interdisciplinary field. Comparing networks of healthy volunteers with those of patients can potentially offer new, quantitative diagnostic methods and a framework for better understanding brain and mind disorders. We explore resting state functional Magnetic Resonance Imaging (fMRI) data through network measures. We construct networks representing 15 healthy individuals and 12 schizophrenia patients (males and females), all of whom are administered three drug treatments: i) a placebo; and two antipsychotic medications ii) aripiprazole and iii) sulpiride. We compare these resting state networks to a performance at an "N-back" working memory task

SUBMITTER: Towlson EK 

PROVIDER: S-EPMC6752631 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature