Monitoring the interplay between transposable element families and DNA methylation in maize.

ABSTRACT: DNA methylation and epigenetic silencing play important roles in the regulation of transposable elements (TEs) in many eukaryotic genomes. A majority of the maize genome is derived from TEs that can be classified into different orders and families based on their mechanism of transposition and sequence similarity, respectively. TEs themselves are highly methylated and it can be tempting to view them as a single uniform group. However, the analysis of DNA methylation profiles in flanking regions provides evidence for distinct groups of chromatin properties at different TE families. These differences among TE families are reproducible in different tissues and different inbred lines. TE families with varying levels of DNA methylation in flanking regions also show distinct patterns of chromatin

SUBMITTER: Noshay JM 

PROVIDER: S-EPMC6752859 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature