Clinical factors associated with bacterial translocation in Japanese patients with type 2 diabetes: A retrospective study.

ABSTRACT:

Objective

To explore clinical factors associated with bacterial translocation in Japanese patients with type 2 diabetes mellitus (T2DM).

Methods

The data of 118 patients with T2DM were obtained from two previous clinical studies, and were retrospectively analyzed regarding the clinical parameters associated with bacterial translocation defined as detection of bacteremia and levels of plasma lipopolysaccharide binding protein (LBP), the latter of which is thought to reflect inflammation caused by endotoxemia.

Results

LBP level was not significantly different between patients with and without bacteremia. No clinical factors were significantly correlated with the detection of bacteremia. On the other hand, plasma LBP level was significantly correlated with HbA1c (r = 0.3

SUBMITTER: Tamaki S 

PROVIDER: S-EPMC6752875 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature