Current state of clinical trials in breast cancer brain metastases.

ABSTRACT:

Background

Breast cancer brain metastases (BCBM) are the final frontier in neuro-oncology for which more efficacious therapies are required. In this work, we explore clinical trials in BCBM, and determine the shortcomings in the development of new BCBM therapies to shed light on potential areas for enhancement.

Methods

On July 9, 2018, we searched ClinicalTrials.gov for all interventional and therapeutic clinical trials involving BCBM, without limiting for date or location. Information on trial characteristics, including phase, status, start and end dates, study design, primary endpoints, selection criteria, sample size, experimental interventions, results, and publications were collected and analyzed.

Results

Fifty-three trials fulfilled the selection criteria. Media

SUBMITTER: Fares J 

PROVIDER: S-EPMC6753353 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature