Contagion models for the transmission of drug abuse among propinquity-of-rearing defined acquaintances: A Swedish national study.

ABSTRACT:

Background

Can we validate a contagion model for drug abuse (DA) in Propinquity-of-Rearing Defined Acquaintances (PRDAs)?

Methods

PRDAs were defined as pairs of same-age males born 1975-1990 who grew up within 2 km of each other, one of whom (PRDA1) being first registered for DA in national registries. Using adult residential location, we predicted, using regression splines, proximity-dependent risk for DA first registration in a second PRDA (PRDA2) within 3 years of PRDA1's registration.

Results

In 181,743 PRDA pairs, the best-fit model, controlling for age and PRDA2 community risk, included 2 slopes of proximity-risk relationships in childhood and three in adulthood. Risk for DA in PRDA2 was strongly predicted by childhood proximity to PRDA1: 0 to 0.5 km - Hazard ra

SUBMITTER: Kendler KS 

PROVIDER: S-EPMC6754117 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature