Association Between Early Hypertension Control and Cardiovascular Disease Incidence in Veterans With Diabetes.

ABSTRACT:

Objective

Guidelines for hypertension treatment in patients with diabetes diverge regarding the systolic blood pressure (SBP) threshold at which treatment should be initiated and treatment goal. We examined associations of early SBP treatment with atherosclerotic cardiovascular disease (ASCVD) events in U.S. adults with diabetes.

Research design and methods

We studied 43,986 patients with diabetes who newly initiated antihypertensive therapy between 2002 and 2007. Patients were classified into categories based on SBP at treatment initiation (130-139 or ≥140 mmHg) and after 2 years of treatment (100-119, 120-129, 130-139, 140-159, and ≥160 mmHg). The primary outcome was composite ASCVD events (fatal and nonfatal myocardial infarction and stroke), estimated using inverse proba

SUBMITTER: Raghavan S 

PROVIDER: S-EPMC6754236 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature