Dengue virus infection in people residing in Africa: a systematic review and meta-analysis of prevalence studies.

ABSTRACT: Better knowledge of the face of the current dengue virus (DENV) epidemiology in Africa can help to implement efficient strategies to curb the burden of dengue fever. We conducted this systematic review and meta-analysis to determine the prevalence of DENV infection in Africa. We searched PubMed, EMBASE, African Journals Online, and Africa Index Medicus from January 1^st, 2000 to June 10^th, 2019 without any language restriction. We used a random-effects model to pool studies. A total of 76 studies (80,977 participants; 24 countries) were included. No study had high risk of bias. Twenty-two (29%) had moderate and 54 (71%) had low risk of bias. In apparently healthy individuals, the pooled prevalence of DENV was 15.6% (95% confidence interval 9.9-22.2), 3.5% (0.8-7.8), an

SUBMITTER: Simo FBN 

PROVIDER: S-EPMC6754462 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature