Fundus Densitometry Findings Suggest Optic Disc Hemorrhages in Primary Open-Angle Glaucoma Have an Arterial Origin.

ABSTRACT:

Purpose

To analyze optic disc hemorrhages (DH) associated with primary open-angle glaucoma by quantifying their geometric profile and comparing their densitometry with hemorrhages from retinal vein occlusions (RVO) and retinal macroaneurysms (MA), which have venous and arterial sources of bleeding, respectively.

Design

Retrospective cross-sectional study.

Methods

Setting: Massachusetts Eye & Ear.

Population

Fundus images of DH (n = 40), MA (n = 14), and RVO (n = 25) were identified. Patient clinical backgrounds and demographics were obtained.

Main outcome measures

Grayscale pixel intensity units of hemorrhages and adjacent arteriole and venule over the same background tissue were measured. Densitometry differentials (arteriole or venule minus hemorrhage

SUBMITTER: Chou JC 

PROVIDER: S-EPMC6754625 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature