Fluoride exposure and kidney and liver function among adolescents in the United States: NHANES, 2013-2016.

ABSTRACT:

Background

Hepato- and nephrotoxicity of fluoride have been demonstrated in animals, but few studies have examined potential effects in humans. This population-based study examines the relationship between chronic low-level fluoride exposure and kidney and liver function among United States (U.S.) adolescents. This study aimed to evaluate whether greater fluoride exposure is associated with altered kidney and liver parameters among U.S. youth.

Methods

This cross-sectional study utilized data from the National Health and Nutrition Examination Survey (2013-2016). We analyzed data from 1983 and 1742 adolescents who had plasma and water fluoride measures respectively and did not have kidney disease. Fluoride was measured in plasma and household tap water. Kidney parameters inclu

SUBMITTER: Malin AJ 

PROVIDER: S-EPMC6754771 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature