Environmental phthalate exposure and preterm birth in the PROTECT birth cohort.

ABSTRACT:

Background

Preterm birth is a global public health issue and rates in Puerto Rico are consistently among the highest in the USA. Exposures to environmental contaminants might be a contributing factor.

Methods

In a preliminary analysis from the Puerto Rico Testsite for Exploring Contamination Threats (PROTECT) cohort (n = 1090), we investigated the association between urinary phthalate metabolite concentrations measured at three study visits (targeted at 20, 24, and 28 weeks of gestation) individually and averaged over pregnancy with gestational age at delivery and preterm birth. We additionally assessed differences in associations by study visit and among preterm births with a spontaneous delivery.

Results

Compared to women in the general USA population, urinary conce

SUBMITTER: Ferguson KK 

PROVIDER: S-EPMC6754790 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature