The Role of Autologous Dermal Micrografts in Regenerative Surgery: A Clinical Experimental Study.

ABSTRACT: The aim of the study was the objective assessment of the effectiveness of a microfragmented dermal extract obtained with Rigenera™ technology in promoting the wound healing process in an in vivo homogeneous experimental human acute surgical wound model. The study included 20 patients with 24 acute postsurgical soft tissue loss and a planned sequential two-stage repair with a dermal substitute and an autologous split-thickness skin graft. Each acute postsurgical soft tissue loss was randomized to be treated either with an Integra® dermal substitute enriched with the autologous dermal micrografts obtained with Rigenera™ technology (group A-Rigenera™ protocol) or with an Integra® dermal substitute only (group B-control). The reepithelialization rate in the wounds was assessed in both groups a

SUBMITTER: Tresoldi MM 

PROVIDER: S-EPMC6754962 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature