Impact of Prescribing on New Persistent Opioid Use After Cardiothoracic Surgery.

ABSTRACT:

Background

New persistent opioid use occurs in 3% to 14% of patients after elective surgery, but is poorly described after cardiothoracic surgery. We examined the association of prescription size with new persistent opioid use after cardiothoracic surgery.

Methods

Opioid-naive Medicare patients undergoing cardiothoracic surgery between 2009 and 2015 were identified. Patients who filled an opioid prescription between 30 days before surgery and 14 days after discharge and with continuous Medicare enrollment 12 months before and 6 months after surgery were selected (n = 24,549). New persistent use was defined as continued prescription fills 91 to 180 days after surgery. Prescription size was reported in oral morphine equivalents. Multivariable regression was performed for risk

SUBMITTER: Brescia AA 

PROVIDER: S-EPMC6755048 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature