Big Data to the Bench: Transcriptome Analysis for Undergraduates.

ABSTRACT: Next-generation sequencing (NGS)-based methods are revolutionizing biology. Their prevalence requires biologists to be increasingly knowledgeable about computational methods to manage the enormous scale of data. As such, early introduction to NGS analysis and conceptual connection to wet-lab experiments is crucial for training young scientists. However, significant challenges impede the introduction of these methods into the undergraduate classroom, including the need for specialized computer programs and knowledge of computer coding. Here, we describe a semester-long, course-based undergraduate research experience at a liberal arts college combining RNA-sequencing (RNA-seq) analysis with student-driven, wet-lab experiments to investigate plant responses to light. Students derived hypothes

SUBMITTER: Procko C 

PROVIDER: S-EPMC6755220 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature