Association of Early-Stage Breast Cancer and Subsequent Chemotherapy With Risk of Atrial Fibrillation.

ABSTRACT:

Importance

Several types of cancer have been linked to a higher risk of developing atrial fibrillation (AF). Fewer data exist regarding early-stage breast cancer (EBC), for which cardio-oncology concerns are more pertinent.

Objective

To investigate the association of EBC and subsequent chemotherapy with the risk of developing AF.

Design, setting, and participants

This was a population-based, retrospective, matched cohort study conducted in Toronto, Ontario, Canada, of 68 113 women diagnosed with EBC between April 2007 and December 2016 who were matched 1:3 to a cancer-free control group based on birth year and receipt of breast imaging. Prevalence of AF before the index date (date of EBC diagnosis) was compared between the cohorts using the McNemar test. Cumulative in

SUBMITTER: Abdel-Qadir H 

PROVIDER: S-EPMC6755537 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature