Effects of Trichophyton mentagrophytes infection on the immune response of rabbits.

ABSTRACT:

Background

Rabbit breeding has developed into a large-scale industry, and as such, the incidence of dermatophytosis in rabbits has become increasingly common. A rabbit model with Trichophyton mentagrophytes infection was established to study the changes within the immune responses after fungal infection.

Methods

After the T. mentagrophytes challenge on skin, pathogens on the skin were isolated from the rabbits in the fungal infection (FI) groups 20 days. Fungal observation under microscope were carried out. Identification of strains was achieved by polymerase chain reaction (PCR) using the CDR1 gene. The collected anticoagulant blood samples were analyzed for various blood cell parameters. The levels of antibodies, including IgM and IgA, cytokines, including IL

SUBMITTER: Xiao C 

PROVIDER: S-EPMC6756135 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature