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Effects of Fasting and Refeeding on the mRNA levels of Insulin-like Growth Factor-binding Proteins in Chick Liver and Brain.


ABSTRACT: The physiological functions of insulin-like growth factor-binding proteins (IGFBPs) in mammals have been evaluated in several studies. However, the physiological roles of IGFBPs in chickens have not yet been elucidated. In this study, we examined the effects of short-term (6 h) fasting and refeeding on the mRNA levels of IGFBPs in chick liver and brain. Eighteen 8-day-old chicks were weighed and allocated to three groups on the basis of body weight, and subjected to ad libitum feeding, 6 h of fasting, or 6 h of fasting followed by 6 h of refeeding. After the chicks were euthanized by decapitation, the liver and brain were excised, and the brain was dissected into six segments (telencephalon, optic lobes, cerebellum, rostral part of the brainstem, middle part of the brainstem, and caudal pa

SUBMITTER: Fujita S 

PROVIDER: S-EPMC6756412 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature