Relative value of cystatin C and creatinine-based estimates of glomerular filtration rate in predicting long-term mortality after cardiac surgery: a cohort study.

ABSTRACT:

Objective

Renal dysfunction predicts an increased risk of both early and long-term mortality after cardiac surgery. Cystatin C enables glomerular filtration rate (GFR) to be estimated accurately and may be superior in this regard to creatinine-based estimates. We hypothesised, therefore, that cystatin C and derived estimates of GFR would independently predict long-term survival after cardiac surgery and would be superior in this respect to traditional estimates of GFR. The current study tests this hypothesis in a large and well-characterised cohort of patients.

Design

A prospective cohort study.

Setting

Regional cardiothoracic centre in Northeast Scotland.

Participants

1010 patients undergoing non-emergent cardiac surgery between 2004 and 2007. Serum creatinine

SUBMITTER: Mooney JF 

PROVIDER: S-EPMC6756440 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature